Rio Branco - Acre
Clinical Research Center Silvestre Santé
High-standard clinical research in a region shaped by the rich diversity of the Amazonian population: fast recruitment, consistent retention and a complete hospital structure at a single address.
- Operating since
- 2019Operating since
- Participants followed
- +2,000Participants followed
- From the international airport
- 18 minFrom the international airport

The Center
Running national and international trials since 2019
Silvestre Santé Research Center runs studies across several therapeutic areas — diabetes, hypertension, respiratory diseases, infectious diseases and cardiometabolic conditions — having followed more than 2,000 participants over this period.

Strategic location
Located in Rio Branco - Acre, in a region shaped by the rich diversity of the Amazonian population, with easy access for monitors, sponsors and participants.
- Rio Branco International Airport
- 18 minutes
- Nearest hotel
- 5 minutes
Demographics and epidemiology
- 900,000
- inhabitants in the state of Acre
- 70%
- mixed-race and 3% Indigenous population
- 23%
- living with obesity — Rio Branco is considered Brazil's obesity capital, according to Vigitel
- A region with a significant incidence of cardiovascular and metabolic diseases.
- High prevalence of infectious diseases: dengue, zika and chikungunya.
- A diverse population whose genetic and environmental profile is under-represented in global trials.
What sets us apart
The only active center in the region
We are the only active clinical research center in Rio Branco and in the state of Acre.
Fast recruitment
Our own patient base and a high clinical volume support rapid screening.
Strong patient retention
Close follow-up and a direct bond between physician and participant.
Multiprofessional team
Investigators, study coordination, nursing, biomedical science, pharmacy and nutrition.
International qualification
Team certified in IATA and GCP, with English proficiency.
Staff backup system
Full operational continuity, even when the unexpected happens.
Facilities
A full hospital at the service of clinical research
We are a hospital with an Emergency Department and laboratory, outpatient, cardiology and imaging exam rooms — all integrated into study operations.
- seats in the reception area
- 100seats in the reception area
- parking spaces
- 120parking spaces
- patients seen per day
- +150patients seen per day
- monitors in the monitoring room
- 10monitors in the monitoring room
Exams performed on site
- X-ray
- CT scan
- Ultrasound
- Echocardiogram
- ABPM
- Holter
- Exercise stress test
- Spirometry

Reception area seating 100 people

Consulting and outpatient rooms

Emergency Department and monitored beds

Imaging room with computed tomography

Cardiology exams: ABPM, Holter and stress testing
Research infrastructure
Spaces dedicated exclusively to clinical trials

Monitoring room
Accommodates up to 10 study monitors, with an adjoining kitchenette for meals.

Workstations
Individual desks for the center's study coordinators.

Blood draw room
A dedicated space for participant sample collection, with privacy and comfort.

Sample processing and collection
Processing, packaging and temperature control of the samples.

Dedicated pharmacy
Controlled, exclusive storage of investigational products.
Team
Our team
Principal investigators, medical specialists, study coordination and research assistants. A qualified, experienced team certified in IATA and GCP, with English proficiency.

Dr. Wilson Rodrigues Barbosa Neto
- Medicine - CRM AC 1918
- Cardiology - RQE 819

Dra. Andréia Barros Pinheiro
- Medicine - CRM AC 1763
- Cardiology - RQE 971

Dr. Eduardo Passos
- Medicine - CRM AC 1656
- Cardiology
- Echocardiography

Dra. Gabriela Cordeiro
- Medicine - CRM AC 1918
- Infectious Diseases - RQE 863

Dr. Carlos Silvestre
- Medicine - CRM AC 1974
- Radiology - RQE 540

Dra. Isabel Braga Paiva
- Medicine - CRM AC 1913
- Ophthalmology - RQE 890

Mariana da Cunha e Silva
- Nutrition - CRN7 9471
- Clinical nutrition

John Herbert Rivas Pinninghoff Junior
- Pharmacy - CRF AC 588313

Paula Dállet dos Santos
Research Manager
- Biomedical Science - CRBM 4 8814
- IATA

Yasmin Soares de Moura
Study Coordinator
- Nursing - COREN AC 969697
- IATA

Dannyelle Mayanne Freire Gama
Study Coordinator
- Biomedical Science - CRBM 4 8233
- IATA

Thaís Giovana Araújo Silva
Study Coordinator
- Biomedical Science - CRBM 4 11084
- IATA

Isabelle Mezerhane
Study Coordinator
- Biomedical Science - CRBM 4 11155
- IATA

Tainá Mendes
Research Assistant
- Nursing

Isadora Salgueiro de Araújo
Research Assistant
- Nursing
Results
Recruitment rankings
Positions achieved by the center in trials conducted in the following areas.
- 1st
COVID-19 and thromboembolism
Cardiology
- 8th
Asthma
Pulmonology
- 1st
Hypertension
Cardiology
- 3rd
Post-COVID-19
Infectious Diseases
- 1st
Dyslipidemia
Cardiology
- 4th
Heart failure
Cardiology
- 8th
Breast cancer and myocardial toxicity
Cardio-oncology
- 1st
High cardiovascular risk
Cardiology
Strategic, efficient recruitment
In-house patient database
An active hospital patient base used for rapid screening of eligible candidates.
Community of referring physicians
A loyal network of referrers engaged with clinical research.
Workshops and scientific events
We strengthen ties with the medical community and broaden the identification of eligible participants.
Word-of-mouth impact
Participant trust continuously attracts new volunteers.
Optimizing patient retention
Humanized care
Clear communication and rapport with the patient at every stage.
Strong physician-patient bond
Direct follow-up by the investigator at every visit.
Dedicated call center
Fast, continuous support for study participants.
Quick issue resolution
Events addressed even outside scheduled visits.
Full patient support
Logistical assistance and immediate team availability.
Experience-focused
Greater engagement and high retention rates throughout the studies.

Manifesto
“Caring for people is our culture.”
Our scientific goal is to contribute to national and international trials conducted with quality, widening the Amazonian population's access to clinical research.
Contact
Get in touch with us
Sponsors, CROs, referring physicians and people interested in taking part in trials can speak directly with the center's team. We respond via WhatsApp, phone or email — no intermediate forms.
Rio Branco - Acre — 18 minutes from Rio Branco International Airport.

